http://WWW.BCGRC.IN
http://WWW.BCGRC.IN

Checking delivery availability...

background-sm
Search
3

Updates found with 'attune nxt acoustic focusing flow cytometers'

Page  1 1

Updates found with 'attune nxt acoustic focusing flow cytometers'

Clog Resistance of non-Pressure Based Flow CytometersBy Greg Kaduchak, PhD10.25.2017Flow cell clogs have been a long standing issue in flow cytometry. The small dimensions of the flow cell and fluidic path are susceptible to clogs especially when using larger or ‘sticky’ cells. In addition, historically, flow cytometer systems have been pressure-based which compounds this issue even more.In pressure-based systems, the particles are transported through the system by applying pressure to the fluid. It is a straightforward method to move the fluids through the small channels. To ensure a smooth delivery of fluids and particles through the flow cell without fluctuations, the systems employ pressure regulators. For those that have used these systems, it is a proven design to deliver particles in a flow cytometer and has been successful over the years. But, in the event of a clog, there is not much these systems can do.Figure 1(a) and (b) show what happens when a clog is encountered in a pressure-based fluidic system. When the system is in normal operation (a), the fluid is pushed through the system a specified pressure. For this example, we have used 7 psi. But, as seen in (b), when a clog is encountered the regulator keeps the system at 7 psi. No additional pressure is exerted to move the clog through the flow cell and the flow stops.Figure 1In contrast, in systems that employ positive displacement to drive the fluidic system (e.g. syringe pumps), the pressure is not held constant. These systems operate by a principle of constant volumetric flow. They are designed for fluid to flow with a specified volume delivery rate regardless of the pressure. An example of such a system facing a potential clog is shown in Figs. 1(c) and (d). As seen, the system operates at the same pressure as the pressure-based system when all is fine. But, once a clog is encountered, the system will build pressure to maintain the volumetric delivery rate. Pressure will build until the clog is displaced.The fluidic system in the Attune NxT Acoustic Focusing Flow Cytometers is based on positive displacement fluid delivery. For the purpose of robust clog removal, the system is outfit with a sensor that monitors the system pressure. When a potential clog is encountered, the pressure is allowed to build all the way up to 60 psi before safely shutting down the system. An additional benefit is used by the Attune NxT Flow Cytometer to keep the flow cell clean: a rinse cycle automatically runs between samples, this clears the sample in the flow cell with excess sheath fluid to prevent any cellular buildup.This feature has made the Attune flow cytometer platforms extremely clog resistant. Its install base has grown considerably since its initial launch more than two years ago, but still only a few clogs have been encountered by users of properly maintained instruments. Due to this resistance to clog, positive displacement systems are great from applications where cells are large and sticky, especially for tissue-based samples.
Send Enquiry
Read More
Harvard Health LetterBuild a better bladderExercises, lifestyle change, medications, and procedures can alleviate incontinence and give you your life back.Published: February, 2016A leaky bladder or a sudden urge to go to the bathroom is uncomfortable andembarrassing. But you can take steps to alleviate the problem. "Some people tell me they would have sought treatment sooner if they'd known it was this simple, " says Dr. Anurag Das, director of the Center for Neurourology and Continence at Harvard-affiliated Beth Israel Deaconess Medical Center.Lifestyle changesOne of the first lines of defense is pill-free and costs nothing: lifestyle change. For urge incontinence (see "Types of incontinence"), you can try timed voiding (urinating on a schedule) and bladder guarding, which teaches you to cope with triggers that set off the urge to go, such as washing dishes or hearing water. "You squeeze your muscles to hold in urine before a trigger, which sends a message to the brain that this is not the time to go, " says Dr. Das. Other lifestyle changes include watching fluid intake; quitting smoking, to reduce coughing and pressure on the bladder; and minimizing bladder irritants such as caffeine, alcohol, and carbonated drinks.Pelvic floor rehabThe pelvic floor muscles aid control of your bladder and bowels. Strengthening these muscles can be helpful to people with stress incontinence (see "Types of incontinence") as well as those with urge incontinence. This is done with Kegel exercises, which involve squeezing and releasing the muscles you use to hold in urine. A physical therapist can help you learn how to do the exercises properly. "The majority of people with urge incontinence will improve with rehab. It may not make it 100% better, but even 75% may be acceptable to many people, " says Dr. Das.MedicationsWhen pill-free measures aren't enough to curb incontinence, medications may help. The most commonly prescribed drugs for urge incontinence are anticholinergics, such as oxybutynin (Ditropan). Side effects can include dry mouth and eyes, headache, constipation, and confusion.Some drugs relieve stress incontinence, such as tricyclics like imipramine (Tofranil) and alpha-adrenergic agonists like pseudoephedrine (Sudafed), which are often found in cold medicines. However, these, too, are limited by side effects, and their effect declines over time. When an enlarged prostate causes overflow incontinence (see "Types of incontinence"), alpha blockers such as doxazosin (Cardura) may help by relaxing the smooth muscle of the prostate. It may take trial and error to find the best drugs with the fewest side effects.ProceduresInjections of botulinum toxin (Botox), a muscle relaxant, are used to treat urge incontinence. "The downside is a higher incidence of urine retention and risk of bladder infection. Some patients won't be able to urinate and may need to use a catheter, " says Dr. Das. Injections of calcium hydroxylapatite (Coaptite) are used to treat stress incontinence by tightening the urethra.A procedure called sacral neuromodulation can help people with urge incontinence. A small device called Interstim is implanted in the lower back to stimulate the sacral nerve, improving both bladder and bowel problems.Surgery sometimes is used for stress incontinence. This involves creating a sling that wraps around a person's urethra. "You don't have to use artificial mesh materials for the sling; you can use the patient's own fascia (muscle lining) if preferred, " says Dr. Das. There is no surgery for overflow incontinence if the bladder muscle does not work. However, in cases of blockage from the prostate, prostate surgery may help.Types of incontinenceStress incontinence occurs mostly in women, and it's often the result of a weakened or stretched pelvic floor from childbirth. The telltale symptom is leakage with pressure or stress on the bladder, such as when laughing or coughing. Stress incontinence is less common in men unless they've had an injury or had their prostate removed.Urge incontinence (overactive bladder) is characterized by an inability to get to the bathroom in time. It's caused by overactive contractions of the bladder muscle that may be related to an enlarged prostate in men; changes to the bladder lining or bladder muscle in postmenopausal women; or a chronic neurological condition, such as multiple sclerosis.Overflow incontinence occurs when there's no room for additional urine because the bladder is not emptying, either because it is blocked or because it isn't working properly because of a neurological disorder or a medication side effect. Overflow incontinence primarily affects men with enlarged prostates. Symptoms include frequent leakage or a feeling of lower-belly fullness. The condition increases the risk for bladder infections because the urine pools in the bladder for long periods of time
Send Enquiry
Read More
3 simple ways to get more restful sleepEven people without insomnia can have trouble getting a good night's rest. Many things can interfere with restorative sleep — crazy work schedules, anxiety, trouble putting down the smartphone, even what you eat and drink.The following three simple steps can help you sleepWhen you wake up in the morning, are you refreshed and ready to go, or groggy and grumpy? For many people, the second scenario is all too common. Improving Sleep: A guide to a good night's rest describes the latest in sleep research, including information about the numerous health conditions and medications that can interfere with normal sleep, as well as prescription and over-the-counter medications used to treat sleep disorders. Most importantly, you’ll learn what you can do to get the sleep you need for optimal health, safety, and well-being.1. Cut down on caffeineCaffeine drinkers may find it harder to fall asleep than people who don't drink caffeine. Once they drift off, their sleep is shorter and lighter. For some, a single cup of coffee in the morning means a sleepless night. That may be because caffeine blocks the effects of adenosine, a neurotransmitter thought to promote sleep. Caffeine can also interrupt sleep by increasing the need to urinate during the night.People who suffer from insomnia should avoid caffeine as much as possible, since its effects can endure for many hours. Because caffeine withdrawal can cause headaches, irritability, and extreme fatigue, it may be easier to cut back gradually rather than to go cold turkey. Those who can't or don't want to give up caffeine should avoid it after 2 p.m., or noon if they are especially caffeine-sensitive.2. Stop smoking or chewing tobaccoNicotine is a central nervous system stimulant that can cause insomnia. This potent drug makes it harder to fall asleep because it speeds your heart rate, raises blood pressure, and stimulates fast brainwave activity that indicates wakefulness. In people addicted to nicotine, a few hours without it is enough to induce withdrawal symptoms; the craving can even wake a smoker at night. People who kick the habit fall asleep more quickly and wake less often during the night. Sleep disturbance and daytime fatigue may occur during the initial withdrawal from nicotine, but even during this period, many former users report improvements in sleep. If you continue to use tobacco, avoid smoking or chewing it for at least one to two hours before bedtime.3. Limit alcohol intakeAlcohol depresses the nervous system, so a nightcap may seem to help some people fall asleep. However, alcohol suppresses REM sleep, and the soporific effects disappear after a few hours. Drinkers have frequent awakenings and sometimes frightening dreams. Alcohol may be responsible for up to 10% of chronic insomnia cases. Also, alcohol can worsen snoring and other sleep breathing problems, sometimes to a dangerous extent. Even one drink can make a sleep-deprived person drowsy. In an automobile, the combination significantly increases a person's chance of having an accident.You can also improve the amount and quality of your sleep by getting regular physical activity and creating and sticking to a regular sleep schedule and routine.Many people find that crossing several time zones makes their internal clocks go haywire. In addition to experiencing headaches, stomach upset, and difficulty concentrating, they may also suffer from fitful sleep.But there's no need to waste time riding out the effects of jet lag. Try these jet lag remedies the next time you travel.When you're traveling shorter distancesIf your destination is just one or two time zones away, it may be possible to wake up, eat, and sleep on your regular home schedule. At your destination, schedule appointments and activities for times when you would be alert at home.When you're traveling longer distancesGradually switch before the trip. For several days before you leave, move mealtimes and bedtime incrementally closer to the schedule of your destination. Even a partial switch may help.During the flight, drink plenty of fluids, but not caffeine or alcohol. Caffeine and alcohol promote dehydration, which worsens the symptoms of jet lag. They can also disturb sleep.Switch your bedtime as rapidly as possible upon arrival. Don't turn in until it's bedtime in the new time zone.Use the sun to help you readjust. If you need to wake up earlier in the new setting (you've flown west to east), get out in the early morning sun. If you need to wake up later (you've flown east to west), expose yourself to late afternoon sunlight.If you're traveling on short notice or you're facing an especially stubborn case of jet lag, ask your doctor about a specially timed dose of melatonin or ramelteon, which can help shift your circadian rhythms. If all else fails, a short course of an over-the-counter or prescription sleep aid may do the trick.
Send Enquiry
Read More
Harvard Medical SchoolControlling your weight is key to lowering stroke riskThere is a lot you can do to lower your chances of having a stroke. Even if you've already had a stroke or TIA ("mini-stroke"), you can take steps to prevent another.Controlling your weight is an important way to lower stroke risk. Excess pounds strain the entire circulatory system and can lead to other health conditions, including high blood pressure, diabetes, high cholesterol, and obstructive sleep apnea. But losing as little as 5% to 10% of your starting weight can lower your blood pressure and other stroke risk factors.Protect your brain: That’s the strategy that Harvard doctors recommend in this report on preventing and treating stroke. Whether you’ve already had a mini-stroke or a major stroke, or have been warned that your high blood pressure might cause a future stroke, Stroke: Diagnosing, treating, and recovering from a "brain attack" provides help and advice.Of course, you'll need to keep the weight off for good, not just while you're on a diet. The tips below can help you shed pounds and keep them off:Move more. Exercise is one obvious way to burn off calories. But another approach is to increase your everyday activity wherever you can — walking, fidgeting, pacing while on the phone, taking stairs instead of the elevator.Skip the sipped calories. Sodas, lattes, sports drinks, energy drinks, and even fruit juices are packed with unnecessary calories. Worse, your body doesn't account for them the way it registers solid calories, so you can keep chugging them before your internal "fullness" mechanism tells you to stop. Instead, try unsweetened coffee or tea, or flavor your own sparkling water with a slice of lemon or lime, a sprig of fresh mint, or a few raspberries.Eat more whole foods. If you eat more unprocessed foods — such as fruits, vegetables, and whole grains — you'll fill yourself up on meals that take a long time to digest. Plus, whole foods are full of vitamins, minerals, and fiber and tend to be lower in salt — which is better for your blood pressure, too.Find healthier snacks. Snack time is many people's downfall — but you don't have to skip it as long as you snack wisely. Try carrot sticks as a sweet, crunchy alternative to crackers or potato chips, or air-popped popcorn (provided you skip the butter and salt and season it with your favorite spices instead). For a satisfying blend of carbs and protein, try a dollop of sunflower seed butter on apple slices.For more information on lifestyle changes you can make to help prevent a stroke, buy Stroke: Diagnosing, treating, and recovering from a "brain attack, " a Special Health Report from Harvard Medical School.Stroke: Know when to act, and act quicklyIdentifying and treating a stroke as quickly as possible can save brain cells, function, and lives. Everyone should know the warning signs of a stroke and when to get help fast.The warning signs of a stroke can begin anywhere from a few minutes to days before a stroke actually occurs. The National Stroke Association has devised the FAST checklist to help determine whether a person is having a stroke.Act FASTIf the answer to any of the questions below is yes, there's a high probability that the person is having a stroke.Face: Ask the person to smile. Does one side of the face droop?Arms: Ask the person to raise both arms. Does one arm drift downward?Speech: Ask the person to repeat a simple sentence. Are the words slurred? Does he or she fail to repeat the sentence correctly?Time: If the answer to any of these questions is yes, time is important! Call the doctor or get to the hospital fast. Brain cells are dying.When stroke symptoms occur, quick action is vital. If you think you or someone with you is having a stroke, call the doctor. Ideally, the person affected should be taken to a hospital emergency room that has expertise and experience in treating stroke as it occurs (called acute stroke). If you or someone you love is at high risk for having a stroke, you should know the name and location of the nearest hospital that specializes in treating acute stroke.The goal of stroke treatment is to restore blood circulation before brain tissue dies. To prevent brain cell death that is significant enough to cause disability, treatment is most effective if it starts within 60 minutes of the onset of symptoms. But it can still be very effective if given within 3 hours of symptom onset.An important goal of ongoing stroke research is to find treatments that can buy time by protecting the person's brain until blood circulation is restored, which can increase the chances of survival and decrease the chances of disability.
Send Enquiry
Read More
Have You Been Diagnosed With An Autoimmune Disease? Medical medium If you or someone you love have been diagnosed with an autoimmune disease, chances are you’ve been told that your body is attacking itself. Hearing this probably stripped you of hope that you can heal and left you feeling betrayed by your own body. Today there are countless mysterious diseases that have been labeled as autoimmune conditions. But the problem is that the concept of autoimmunity is inherently flawed and this mistaken theory only hurts you and your loved ones in the end. Surprised? When we believe our own bodies are attacking themselves, we are unknowingly hindering our healing process. Our immune systems can weaken in the absence of this truth: Your body never attacks itself. It’s always working for you and loves you unconditionally. It’s never been more critical for you and your loved ones to know and feel this truth in your heart. It will greatly support you and those you care about to heal. Continue reading to learn more and check out the accompanying radio show to further immerse yourself in truth.When medical science and research do not know what is causing symptoms, such as mysterious rashes, mysterious dizziness, mysterious fatigue, mysterious aches and pains, or mysterious inflammation, it gets labeled as an autoimmune issue. This is a mere theory that was initiated in the 1950s and has since been grandfathered in to modern medicine and collectively agreed upon as law. There was a discovery of an antibody but no one had any idea of what it was or what it was for. There were theories and ideas of what it was, but they were just that: theories. One of those theories was that the antibody was there to destroy healthy cells. This theory came about because researchers didn’t have an answer as to what was causing chronic illnesses and symptoms or even an answer to what the antibody was for. Instead the blame was put on those with chronic illness and our bodies became the scapegoat. Better to blame it on our bodies than to blame it on the medical industry and research and science not having the answers. The theory of autoimmune conditions and diseases became a catch-all explanation for dozens of conditions and symptoms that medical communities don’t yet have answers for. When someone is diagnosed with Hashimoto’s, they are told their body is creating antibodies that are destroying their thyroid tissue. With eczema and psoriasis, you will likely be told your body is attacking your skin. If you have lupus, you will likely be told your body is attacking itself and that’s what creates all the inflammation. This same theory is used for countless other chronic illnesses. This is the best explanation that modern medicine has to offer about mysterious diseases today. It’s never been more important for you to know this isn’t accurate because it affects your ability to heal. Not only are you given incorrect information about your health problems, you’re also told your body has turned against you when nothing could be further from the truth. The information I am sharing with you here is meant to free you of the misguided notion that your body would ever attack itself and to reveal the true cause of mysterious diseases that have been labeled autoimmune disorders.The True Causes of Autoimmune DiseasesIf you have an illness that has been labeled as an autoimmune disease, your body truly is attacking something, but it is not attacking itself. As I said, your body is working for you every single day. It works tirelessly for you and is doing the very best it can. When you are sick and have mysterious symptoms, such as fatigue, butterfly rashes, dizziness, tremors, vertigo, aches and pains, digestive trouble, weight loss, insomnia, weight gain, memory loss, numbness, tingling, blood sugar issues, brain fog, mood swings, night sweats, loss of appetite, and many others, it means there is an invader in your body. The same is true if you have lupus, Hashimoto’s, Grave’s, Addison’s, Type 1 Diabetes, colitis, vitiligo, celiac, eczema, Graves’, chronic fatigue syndrome (CFS), myalgic encephalomyelitis (ME), rheumatoid arthritis, fibromyalgia, Lyme disease, multiple sclerosis, parkinson’s, alopecia, or any other disease that is considered to be in the autoimmune category. There is a pathogen invader in your body that it’s working hard to attack and get rid of.Modern medicine has yet to come to this conclusion about mysterious illnesses due to a few reasons. First of all, this theory about the body attacking itself has become law inside the minds of well-intentioned doctors and health professionals who are just doing their best to provide care for their patients. No one is willing to question it because they have come to believe it is the truth, even though there is no evidence backing it.Another reason is because there is no incentive to look into these mysterious diseases. When there is already an acceptable answer that seems to fit, there doesn’t appear to be a need to spend more money on research that they assume will get them nowhere. And finally, even if doctors were to seriously look for these pathogens in their patients coming into their offices with a long list of mysterious symptoms, they would come up dry. Most tests the blood lab offers cannot detect the viruses and bacteria that are invading so many people and causing so many conditions and symptoms. Many of the pathogens causing autoimmune labeled illnesses are yet to be discovered and classified; therefore, it would be quite impossible to detect. You can’t find something when you do not know what you are looking for. For example, medical communities believe there is only one Epstein-Barr virus (EBV)—the virus that causes mono—but in truth there are 61 strains of EBV that cause all kinds of different symptoms and illnesses. I revealed this truth in my book Medical Medium. You can read more about EBV and how it creates illnesses, including cancer, in my book Thyroid Healing.If the medical industry was willing to put more money into researching pathogens, it would be more likely that answers would be coming out in literature today. Viruses and bacteria would be called by name and accurate tests would be created and administered. However, the most popular answer medicine has at the moment is that the body is attacking itself and as I have shared, this is not the truth. The second most popular answer is that it’s your faulty genes causing disease, which is a theory that’s quickly on the rise and still not the answer. In fact, people are told their body is attacking itself and that their genes are the problem.The First Barrier to DestroyThe biggest barrier obstructing your path to true healing is this belief that the body is attacking itself. It may have been ingrained into you not only by your medical practitioners, but also by what you read on the Internet. You are told there is very little you can do to manage your symptom or condition, and nothing you can do to reverse it. This is a lie and something that should be discarded immediately not that you know the truth.Know this: Your body is not attacking itself. I have already said it multiple times in this article, but I must say it over and over until we all understand it deep within our beings. It’s that fundamentally important. Your body is not self-destructive. And your body is not searching out healthy blood cells to harm and kill off. In fact, your body is doing the opposite. Every day your body is working for you. It is on your side. Your immune system cannot do one thing to harm a single cell in your body. It has never been able to do that, and it never will do that. When we know this deep within our being and replace the lie with this truth, something begins to change. That barrier that was once in your way is obliterated, and your path to healing becomes clear and unhampered. It may seem like a small switch, but it is in fact very significant. When your mind is aware that it is a pathogen you are going after, a revelation clicks into place and your body begins to work even more efficiently to kill off that virus. Your immune system fires up and kicks into gear to work for you even harder. This is essential to understand. The power of knowing the truth cannot be underestimated, especially when it comes to healing from these diseases that have plagued so many people for so many years. If you know your body is working for you, it works for you even more. Recovery is finally possible when you are armed with real information that is not hiding behind funding agendas and the bureaucracy of the medical world. This simple understanding sends a message to your body to start breaking down the pathogen fast. And when you start robbing food from the pathogen, which I discuss in the section about healing foods, recovery is even faster. Triggers vs. CauseThere are many medical professionals these days that are offering advice on how to manage your autoimmune disease. Some of this advice discusses “triggers” related to your illness but ironically it’s not even the correct triggers. For example, some experts are just beginning to say that EBV is a trigger for thyroid disease. This is because the never before known information that I have released has forced experts to look at EBV as a possible concern, but this has only led these experts to say that EBV could be a trigger. But in fact, EBV is not a trigger, it is the direct cause. This is a critical distinction that must be understood.The reason we need to make a distinction between trigger and cause is because when we just manage our illness by avoiding triggers, we are not actively fighting the pathogen and addressing the root cause. And if today’s medical professionals and experts believe that EBV is possibly just a trigger but have no idea how to rid the EBV out of the body, then they’re not helping people to heal. We want to do everything we can to kill off the virus invading our body. When we simply just avoid triggers, for example gluten, the virus that’s really behind your suffering can cause further issues. And obviously, we want to do everything we can to ensure the pathogen does not proliferate and cause more symptoms again. Plus, not all triggers can be avoided. We all eventually lose a loved one for example, and the grief we experience can trigger illness if the cause hasn’t been addressed. Or we’re not choosing the right triggers we can avoid. When we recognize the true cause of our illness, we can start to move toward true and total recovery, which is something I’ve witnessed tens of thousands of people doing over the years with the information I’ve shared, and now many more.Let’s take a look at some of the illness labeled as autoimmune diseases and conditions.LupusMedical science and research are unaware that lupus is a viral condition, specifically it is the body reacting to Epstein-Barr’s byproducts and neurotoxins. Medical science and research are completely unaware of this true cause. In fact, lupus is not even diagnosable. It is only visibly diagnosed by inflammation markers. I share more about the undiscovered true cause of lupus in Thyroid Healing.Multiple Sclerosis (MS)With this autoimmune labeled condition, EBV is in the body feeding on high levels of toxic heavy metals. It is not always lesions on the brain that are causing MS symptoms. Many people have spots that show up on brain scans, and they do not have any of the symptoms related to MS. There is so much that is going on in people’s brains: calcifications, crystallizations, dark spots, white spots, heavy metal deposits, MSG deposits, and chemical solvent stains. This does not mean someone has MS. What is actually causing the MS is EBV in addition to the heavy metals—a truth that medical communities are unaware of.Hashimoto's ThyroiditisEBV is also the true cause of Hashimoto’s thyroiditis. The thyroid becomes inflamed because the virus has infected it. Your immune system is not going haywire or out to get you. It’s this virus that’s causing the damage and making you feel miserable. Your body just needs the proper support, which I describe in Thyroid Healing, to triumph over the virus.CeliacCeliac is not a genetic disease. It is inflammation in the intestinal lining from streptococcus bacteria. Medical communities believe that celiac is an autoimmune condition and that it’s limited to a sensitivity to gluten. Rather, wheat gluten is one trigger to this inflammation of the intestinal tract by feeding the strep bacteria in there.Type 1 DiabetesType 1 diabetes occurs when there is an injury to your pancreas. If you have type 1 diabetes, at one point some of your pancreatic tissue was injured from a viral condition or toxic bacteria. Your body is not attacking your pancreas.Grave's DiseaseIn Grave’s disease, a mutated variety of EBV is causing inflammation, which is scarring the thyroid. There are specific unknown varieties of EBV that prompt the thyroid gland to produce more tissue and, as a result, more thyroid hormones. Find out more about Grave’s in Thyroid Healing.Hepatitis A, B, C, DAll versions of hepatitis are viral conditions from the herpetic family, mainly the Epstein-Barr Virus. They are at different stages of what the virus is doing to the liver. Autoimmune hepatitis is a mistake all on its own because medical research doesn’t actually know the true cause of these conditions. They merely see inflammation and antibodies and make the conclusion that the antibodies are going after the liver. However, the immune system is creating these antibodies to help you go after the virus.Mysterious Skin RashingMany varieties of mysterious skin rashing is from the shingles virus. Specifically, eczema and psoriasis can be a combination of EBV and shingles, both in the liver, feeding off of high levels of copper and DDT. The reason mysterious skin rashing does not get diagnosed as shingles is because when something does not look like textbook shingles, they would never think to call it that. However, what modern medicine is unaware of is that there are over 31 varieties of the shingles virus that they have yet to discover. Therefore, it would be impossible to diagnose it as such without further research. Ehler's-Danlos SyndromeEhlers-Danlos syndrome is another example of an illness that has been labeled as autoimmune simply because medical professionals are unaware of the true cause. The truth is that this condition is caused by a virus that’s injuring connective tissue; it’s not genetic.FibromyalgiaThe aches, pains, tenderness, fatigue, and stiffness of fibromyalgia are a result of EBV’s neurotoxins creating chronic inflammation of both the central nervous system and nerves throughout the body. Knowing the true cause means that you can begin to implement the steps needed to allow for healing. You can find out more about fibromyalgia and many other autoimmune diseases and condition in Thyroid Healing.Viruses EatNow that you know that your body is not attacking itself, but rather that it is attacking a pathogen in your body, you can move onto the next step toward healing. The next thing that’s important for you to know is a truth about viruses that science has yet to discover: viruses eat. Modern medicine is still oblivious to the fact that viruses must eat in order to grow and proliferate. Without their favorite foods, viruses will die. Therefore, logically we must know which are their favorite foods and eliminate them from your diet so the virus can exit your system, leaving you free of your symptoms over time.As an example, eczema is due to a virus in the liver. And that virus feeds off certain foods, which then creates an internal dermatoxin that leaches out from the liver, goes into the bloodstream, and then surfaces through the skin. When you know this is the real cause, you can take away the foods the virus likes best.In my book Thyroid Healing I explain in depth how the Epstein-Barr virus feeds, what it feeds on, and how it excretes when it feeds. For example, EBV feeds on toxic heavy metals, as well as all pesticides, including old ones such as DDT stored in the liver, and certain foods we eat. In the book, I explain the entire process of this particular virus as it feeds, excretes, develops, and continues to feed.Viruses Love Heavy MetalsViruses love to feed off of heavy metals, such as mercury, arsenic, cadmium, lead, nickel, alloys, steel, aluminum, and copper, that are in our systems, including in our liver. Heavy metals are not the cause of your autoimmune labeled disease. They simply feed the viruses that are the cause. The good news is you can take active steps to eliminate these metals from your body by eating the five heavy metal detox foods I recommend every day within a 24-hour period. These foods are wild blueberries, Hawaiian spirulina, barley grass juice extract powder, cilantro, and Atlantic dulse. All five of these foods work together to slowly eliminate the heavy metals. Find out how you can incorporate these foods in Thyroid Healing.Many people believe chlorella is actually better for you than spirulina, but chlorella simply does not eliminate heavy metals the way spirulina does. Chlorella drops the metals instantly, while spirulina holds onto them and in tandem with the other key foods, effectively aids in the process of removing them from the body.Foods that Viruses LoveEggs may be considered the perfect food in some circles, but in reality, they are the perfect food for viruses. They essentially incubate viruses, making them stronger and more aggressive. Stay away from eggs if you have a disease that is labeled as autoimmune, especially lupus and PCOS. Unknown to medical communities, eggs are disastrous for those who have ovarian issues. Eggs feed every single virus and bacteria that create conditions that are thought to be autoimmune diseases.Even if you are eating cage-free, natural eggs, these still act as food for pathogens. Viruses look for egg material in the body to feed on. They feed on the natural hormones that are in eggs, which act as a steroid for the virus. It does not matter what kind of eggs you get because unfortunately all eggs feed viruses.In a very similar way, all dairy products feed viruses. Some doctors are knowledgeable about the allergy concern of eating dairy, but we have to recognize that simply eliminating dairy is not enough. We need to understand why we are eliminating it. It’s critical to stop eating foods like dairy and eggs if you have any symptoms or a chronic illness so that they do not continue to feed the pathogens that are causing your symptoms. It is also a good idea to stay away from all corn products and canola oil. These are in almost every packaged food out there, even organic ones, so be mindful of what is in the ingredients list. If it is intimidating to you to avoid these ingredients that seem minor, think of it this way. The more fresh fruits and vegetables you include in our diet, the more apples, sweet potatoes, salads, bananas, and squash, the less room you have in diet for processed foods that likely contain ingredients you are trying to avoid. Think of crowding out your plate with so much good stuff that the packaged foods simply do not have as much space. Also, the more fresh fruits and vegetables you eat, the more you crave them. Keeping this in mind will help you increase your whole foods intake because you know that the more you do it, the easier it will get. It’s also helpful to reduce animal protein while you’re healing because, again, we need room for the fruits, leafy greens, and vegetables, the secrets weapons, as I like to call them. If you like to eat animal protein, try not to eat it three times a day. Instead eat it once a day and find other filling options to enjoy. Instead of chicken on your salad, add black beans, avocado, sweet potato, or hummus. Instead of bacon with your toast, bake potato fries with lots of herbs of spices. And when you do eat animal proteins, choose the cleanest meats possible. Wild fish is one of the better choices. When healing from chronic illnesses and symptoms, it’s helpful to minimize added fats in the diet to allow the liver to cleanse and toxins and viruses to be most effectively purged from the body. One easy way to cut down fats is to stay away from or minimize oils, even olive oil and coconut oil. A small drizzle here or there is fine, but do not overdo the oils. The same goes for other fat sources like nuts for example. Eat just a few with lots of fresh veggies versus having a large portion of nuts.Foods that Fight PathogensThere are so many amazing powerhouse foods that you can eat in order to give your body an extra boost when fighting off pathogens. The first group we can focus on is cruciferous vegetables. There is a misconception circulating around that cruciferous vegetables, also called brassicas, are harmful because of the goitrogenic compounds in them. We are being told to stay away from kale, broccoli, cauliflower, and brussels sprouts, but this is a misguided and unproductive trend. These foods are actually incredible for anyone with an illness that has been labeled as an autoimmune disease, including thyroid conditions. Cruciferous vegetables cannot harm you. They contain phytochemicals that actually fight the bug you are trying to get rid of. These foods can be some of your greatest allies in your path to healing, and it would be wise to include them, both raw and cooked, on a daily basis.Straight cucumber juice is something that can be included daily in order to flush out toxins from the body. Straight celery juice is also important to include because its mineral salts clean up the liver, build up hydrochloric acid, and strengthen bile so you can break down bacteria and viruses in the intestinal tract that cause conditions like colitis, celiac, and crohn's disease. I share recipes for these foods and juices in my book Thyroid Healing.Include plenty of squash in your diet. There are so many delicious varieties to enjoy, such as butternut, kabocha, spaghetti, and acorn. Also, remember to eat lots of fresh herbs like cilantro, rosemary, and thyme. Eat plenty of salads with red leaf lettuce, butter lettuce, arugula, parsley, and radishes. Radishes are a miracle food when fighting off pathogens. Radish greens kill off viruses, and the radishes themselves push poisons out of the body and support the thyroid.Eating plenty of fruit is one of the best ways you can support your healing. If you are afraid of fruit, know that fruit cannot feed candida and fruit sugar isn’t bad for you. It’s the opposite—fruit is the most healing food on earth! So eat plenty of apples, bananas, oranges, and berries. Melons are wonderful for flushing out poisons that the virus creates. Bring in more tropical fruits like papaya, pineapple, and passionfruit if you are able to find them. Eat the fruits that are in season like pears and persimmons in the fall and peaches and plums in the summer. Fruit is an amazing antiviral food that is essential to include when you are fighting a pathogen such as Epstein-Barr virus that is causing your mystery illness. Bananas in particular are great for killing off pathogens in the intestinal tract. If you fear fruit, check out my chapter on Fruit Fear in my book Medical Medium.Another power food that is worth seeking out is dandelion greens. These are often sold at farmers markets and health food stores among other greens like kale and collard greens. Dandelion greens are particularly supportive for the liver because they work to push out poisons that are created from a virus or bacteria. There are so many wonderful herbal teas to include, as well. Nettle leaf and lemon balm are two particularly powerful ones that fight viruses. There is a phytochemical in lemon balm that helps you go after the virus you want to kill. Many people know that nettle leaf tea is anti-inflammatory, but they do not know why. The reason is because it’s killing the pathogens that are creating the inflammation in the first place. When you are drinking your herbal teas with this knowledge, the properties become that much more powerful.In the same way, people are aware that turmeric is anti-inflammatory, but they do not know why. Turmeric has phytochemicals that are poisonous to the bugs that are inflaming people’s joints and backs. This herb is attacking viruses and bacteria.SupplementsIncorporating supplements is critical to fighting off the viruses that are causing your autoimmune disease. As I always recommend, talk to your medical practitioner before you begin taking supplements so you can work together to find the right dosages. Bring your doctor this information and work together to fight the virus with these powerful herbs and supplements. Be sure to get the right supplements. I have a list of preferred supplements that you can find on my website. ZincZinc deficiencies are rampant and can trigger an autoimmune condition. Simply taking zinc can be a huge step toward healing and can be critical for anyone suffering from the symptoms associated with autoimmune diseases. When you take zinc sulfate, it goes directly to where the virus is and starts working on stopping it in its tracks. Additionally, zinc increases your immune system’s ability to fight. B12 with adenosylcobalamin & methylcobalaminMany people are recommending B12 today, which is good. However, there is still very little talk about the right kind of B12. When fighting a viral condition, it is essential to use a combination of both adenosylcobalamin and methylcobalamin. Including a methylfolate supplement along with this specific B12 is especially helpful. Vitamin CWhen fighting a viral condition, it’s important to include some vitamin c supplements, particularly the liposomal c. The Liposomal c I recommend on my preferred supplements page does not contain any corn, which feeds viruses, unlike other brands. Ester C is also very helpful.
Send Enquiry
Read More
MEDICAL DEVICESGecko Biomedical CEO: We are more than a vascular sealant companyBy ARUNDHATI PARMARGecko Biomedical has developed a viscous polymer that can be used in various tissue reconstruction applicationsParis-based Gecko Biomedical began life as a vascular sealant company in December 2013 and CEO Christophe Bancel is now attempting to do a makeover. He would rather the French company be known as a tissue reconstruction company with an ability to produce a polymer that could be used in a variety of medical device applications.In an interview earlier this year in San Francisco, Bancel said the original technology came from MIT and Bob Langer’s lab and the first application is as a vascular sealant in tissue reconstruction. The polymer that Gecko has created have good adhesion capabilities, Bancel, who is also the founder, said. Hence the name Gecko. The green reptile has special, sticky toes that allow it to climb steep walls and be able to be suspended upside down.But now the goal is to use this new chemistry and build the industrial capability to produce the polymer en masse. And then use that to develop new applications in tissue reconstruction either solely or in partnership with larger medical device companies“Our polymers are made up of 3 monomers and you can play with the ratio, ” Bancel explained, adding that different proportions can lead to distinct properties. “We want to be involved in nerve reconstruction and nerve repair [for example].”So what are some of those polymer properties, especially in the vascular sealant space? Here’s how Bancel, who speaks with a decidedly French accent but is completely intelligible, described them:They are bioresorbable and fully hydrophobic so when you apply them inside the body, they don’t react with blood. They don’t get diluted.They only polymerize when you trigger a stimulus. In Gecko’s case, the stimulus is the light. Until you shine the light, the polymers stay the same.It looks like honey and is viscous. Because it’s viscous it doesn’t flow away so it’s very easy to apply and to use it during surgical procedures.Of competitors in the sealant market, Bancel wasn’t too worried.“You have products that have sealant functionality but not the way we do it, ” he declared, noting that current vascular sealant products in the marketplace are either fibrin-based or bovine, albumin-based.“The fibrin-based sealants and the bovine-based sealants they can get diluted by blood or water when doctors use it, ” Bancel said. “They are very liquid so they spill away. Their products become polymerized as soon as you mix them. In our case, the surgeon completes the procedure and within seconds the product moves from its unpolymerized liquid, viscous state into a polymerized, solid yet flexible state. So the doctor has full control.”If and when the sealant product, which has CE Mark, is launched in the U.S., Gecko would be taking on companies like Ethicon, part of Johnson & Johnson; CR Bard, Baxter, Cohera Medical and others.But the company does not intend to be a one-trick pony.“What is important is that we have been known as a company with a new sealant application, but this was just the tip of the iceberg, ” Bancel declared. “If we are working in vascular, cardiac, nerve, bone, ophthalmology, Gecko becomes an open R& D ecosystem on a proprietary technology. We [can] start to engage on a program that we develop by ourselves and now start to do designing for third parties — for larger medtechs.”He declined to identify who those larger medtechs are or could be.Gecko has raised 8 million euros in 2013 and 22.5 million euros in 2016. For its Series B, the company is planning to raise around $40-50 million. The product has CE Mark but will require undergoing a premarket approval process here in the U.S. to go through the FDA. The company hopes to file an investigational device exemption and begin selling next year.
Send Enquiry
Read More
Stem cell PortalMarch 21, 2018Mending broken hearts with cardiomyocyte moldsWhether caused by an undetected birth defect or by a heart attack (myocardial infarction), when a heart sustains damage it can be difficult to repair.If heart muscle cells — cardiomyocytes — could be repaired by cells taken from one’s own body, the patient's recovery improves. But manufacturing heart cells requires an exacting process tailored specifically to an individual.In a study published recently in Advanced Functional Materials, a team of researchers at Michigan Technological University in collaboration with Harvard Medical School shows how cardiomyocytes grown in a heart-like environment mature more quickly, have improved functionality and are less likely to be rejected by patients’ bodies.Many people with heart injuries from heart attacks or birth defects could benefit from the “self-therapeutic” process of injecting healthy cells into the damaged heart muscle. Labs use induced pluripotent stem cells (iPSCs), which using biochemical cues can be “programmed” to become any type of cell, whether for the heart muscle or otherwise. Yet current processes result in underdeveloped cells.To date, manufacturing cardiomyocytes has occurred in two-dimensional settings (essentially, petri dishes). But the growth environment plays a large role in the ways the cells develop. Thus, simulating the actual heart environment — with lots of pressure and specific forces acting on the growing cells — could lead to more robust cardiomyocytes.“Unfortunately stem cell therapeutics don’t have high success rates, partly because the cells are not mature and fully functional. The maturation and functionality are essential, ” said Parisa Pour Shahid Saeed Abadi, Ph.D., assistant professor of mechanical engineering, whose work in creating heart cell growth environments is detailed in the study.Mimicking the natural heart environmentDr. Abadi and her co-authors have created three-dimensional substrates — essentially, molds — that recreate the environment in which heart cells grow inside the human body. Biomechanical properties the substrates induce include pressure and stiffness.“The mechanical properties of substrates play an important role in the cell behavior because the mechanical cues that cells sense in the actual (heart) environment is unique, ” Dr. Abadi said. “We are using biochemical and biomechanical cues to enhance the differentiation and maturation. If we don’t take advantage of the physical cues and only rely on chemical cues, the process suffers from low efficiency and batch-to-batch inconsistency.”Using photolithography and reflow processing, Dr. Abadi’s substrates are patterned at the micron and submicron levels, approximating the natural physical forces cells experience. Photolithography uses ultraviolet light to remove portions of polydimethylsiloxane (PDMS) substrate to mold it into cylindrical shapes.Additional micro-patterning of the substrate changes the cytoskeleton in the cell and the shape of the nucleus, which cause the genes in the cell to change. As the cardiomyocytes mature, they beat stronger and resemble the cells found in natural, mature heart muscle.“On day one we start seeing the effect of the substrate on the morphology of the cells, ” Dr. Abadi said.Abadi’s lab continues to improve the substrate preparation methods. As cardiomyocytes need to communicate with each other during their growth, Dr. Abadi also plans to stimulate electrical conductivity between cells. Translational studies in animals are the next step for the research.These lab-fabricated, fluorescently stained cardiomyocytes — heart muscle cells — exhibit the maturation and functionality of heart cells grown within a heart.Induced pluripotent stem cell-derived cardiomyocytes beating in substrate.
Send Enquiry
Read More
Page 1 1